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Methylprednisolone succinate

Name: Methylprednisolone succinate
Brand: TargetMol
SKU: T22367
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22367Cas No. 2921-57-5

Alias Methylprednisolone hydrogen succinate, Methylprednisolone hemisuccinate

Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.

Methylprednisolone succinate

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Purity: 99.82%

Catalog No. T22367Alias Methylprednisolone hydrogen succinate, Methylprednisolone hemisuccinateCas No. 2921-57-5

Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$38	In Stock	In Stock
50 mg	$64	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.82%

Appearance:Solid

Color:White

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COA HPLC LCMS HNMR

Product Introduction

Methylprednisolone succinate AI Summary

Methylprednisolone succinate exhibits activity in FDA HLAED liver enzyme composite assays, showing both active and marginal composite activities. Additionally, it demonstrates bioactivity in a biochemical firefly luciferase enzyme assay for NPC with a potency of 40533.4 nM, indicating potential activity in this specific enzymatic pathway. However, it shows no significant bioactivity as an agonist or antagonist in various other in vitro assays targeting different receptors and enzymes, indicating a limited range of meaningful interactions or effects on the biological targets tested..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.
Synonyms	Methylprednisolone hydrogen succinate, Methylprednisolone hemisuccinate

Chemical Properties

Molecular Weight	474.54
Formula	C₂₆H₃₄O₈
Cas No.	2921-57-5
Smiles	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)COC(=O)CCC(O)=O)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
Relative Density.	1.33g/cm3

Storage & Solubility Information

Storage

store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (200.19 mM), Sonication is recommended.

Ethanol: 3 mg/mL (6.32 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (6.95 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1073 mL	10.5365 mL	21.0730 mL	105.3652 mL
5 mM	0.4215 mL	2.1073 mL	4.2146 mL	21.0730 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.2107 mL	1.0537 mL	2.1073 mL	10.5365 mL
20 mM	0.1054 mL	0.5268 mL	1.0537 mL	5.2683 mL
50 mM	0.0421 mL	0.2107 mL	0.4215 mL	2.1073 mL
100 mM	0.0211 mL	0.1054 mL	0.2107 mL	1.0537 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc