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Anti-PSGL-1/CD162 Antibody-APC (9H297)

🥰Excellent
Catalog No. TMAY-02649A

Anti-PSGL-1/CD162 Antibody-APC (9H297) is a APC-conjugated Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody-APC (9H297) can be used in FCM.

Anti-PSGL-1/CD162 Antibody-APC (9H297)

Anti-PSGL-1/CD162 Antibody-APC (9H297)

🥰Excellent
Catalog No. TMAY-02649A
Anti-PSGL-1/CD162 Antibody-APC (9H297) is a APC-conjugated Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody-APC (9H297) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-PSGL-1/CD162 Antibody-APC (9H297) is a APC-conjugated Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody-APC (9H297) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
9H297
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human SELPLG(CD162) expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human SELPLG(CD162). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human PSGL-1 / CD162 / SELPLG (rh PSGL-1 / CD162 / SELPLG; TMPY-03531; Q14242-1; Met1-Gly295) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundP-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Human PSGL-1 / CD162 / SELPLG Protein (TMPY-03531)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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