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Arg-Gly-Asp TFA (99896-85-2(free base))

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Catalog No. T4613
Alias RGD Trifluoroacetate, RGD

Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

Arg-Gly-Asp TFA (99896-85-2(free base))
Other Forms of Arg-Gly-Asp TFA (99896-85-2(free base)):

Arg-Gly-Asp TFA (99896-85-2(free base))

🥰Excellent
Purity: 99.2%
Catalog No. T4613Alias RGD Trifluoroacetate, RGD
Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$35In StockIn Stock
10 mg$59In StockIn Stock
25 mg$101In StockIn Stock
50 mg$151In StockIn Stock
100 mg$226In StockIn Stock
200 mg$339In StockIn Stock
1 mL x 10 mM (in DMSO)$55In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.2%
Color:White
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Product Introduction

Bioactivity
Description
Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
In vitro
RGD Trifluoroacetate is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. There are 24 integrins binding to ECM molecules in a RGD dependent manner: α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1[1].
SynonymsRGD Trifluoroacetate, RGD
Chemical Properties
Molecular Weight460.36
FormulaC14H23F3N6O8
SmilesOC(=O)C(F)(F)F.NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC(O)=O)C(O)=O
Relative Density.no data available
SequenceH-Arg-Gly-Asp-OH
Sequence ShortRGD
Storage & Solubility Information
Storagekeep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (119.47 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1722 mL10.8611 mL21.7221 mL108.6107 mL
5 mM0.4344 mL2.1722 mL4.3444 mL21.7221 mL
10 mM0.2172 mL1.0861 mL2.1722 mL10.8611 mL
20 mM0.1086 mL0.5431 mL1.0861 mL5.4305 mL
50 mM0.0434 mL0.2172 mL0.4344 mL2.1722 mL
100 mM0.0217 mL0.1086 mL0.2172 mL1.0861 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

IntegrinArg-Gly-Asp TFA (99896-85-2(free base))ArgGlyAsp TFA (99896852(free base))Arg Gly Asp TFA (99896 85 2(free base))
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