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Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 2 (Synonyms: p-Merlin (Ser518), p-Merlin (S518), Merlin (p-Se...)
Catalog No. TMAC-02562 Copy Product Info
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Anti-Phospho-Merlin (Ser518) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Merlin (Ser518). Anti-Phospho-Merlin (Ser518) Polyclonal Antibody can be used in IF,WB.
Anti-Phospho-Merlin (Ser518) Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAC-02562
Synonyms p-Merlin (Ser518), p-Merlin (S518), Merlin (p-Ser518), Merlin (p-S518)
Anti-Phospho-Merlin (Ser518) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Merlin (Ser518). Anti-Phospho-Merlin (Ser518) Polyclonal Antibody can be used in IF,WB.
Anti-Phospho-Merlin
(Ser518) Polyclonal Antibody 2
(Ser518) Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-Merlin (Ser518) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Merlin (Ser518). Anti-Phospho-Merlin (Ser518) Polyclonal Antibody can be used in IF,WB. |
| Synonyms | p-Merlin (Ser518), p-Merlin (S518), Merlin (p-Ser518), Merlin (p-S518) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from HUVEC cells untreated (lane 1) or treated with IFN-a (lane 2) using Merlin (Phospho-Ser518) Antibody TMAC-02562. 2. Immunofluorescence staining of methanol-fixed Hela cells using Merlin (Phospho-Ser518) Antibody TMAC-02562. 3. Western blot analysis of extracts from C6 cells, treated with calf intestinal phosphatase (CIP), using Merlin (Phospho-Ser518) Antibody TMAC-02562.    |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 518 (R-L-S(p)-M-E) derived from Human Merlin |
| Antigen Species | human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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