CNTF Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.9 kDa and the accession number is P20294.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 μg | 5 days | $ 165.00 | |
100 μg | 5 days | $ 618.00 | |
1 mg | 5 days | $ 3,600.00 |
Description | CNTF Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.9 kDa and the accession number is P20294. |
Species | Rat |
Expression System | E. coli |
Tag | Tag Free |
Accession Number | P20294 |
Synonyms | ciliary neurotrophic factor |
Construction | The Rat CNTF (P20294) (Met 1-Met 200) was expressed and purified. |
Protein Purity | > 92 % as determined by SDS-PAGE |
Molecular Weight | 22.9 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 0.1M NaCl, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its actions appear to be restricted to the nervous system. Ciliary neurotrophic factor (CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracellular CNTF binding subunit (CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocyteands may be relevant in reducing tissue destruction during inflammatory attacks. CNTF also is a survival factor for neurons of the peripheral sensory sympathetic and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors. |
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CNTF Protein, Rat, Recombinant ciliary neurotrophic factor recombinant recombinant-proteins proteins protein