Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)

Catalog No. TMPJ-00475 Copy Product Info

Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.

Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)

Catalog No. TMPJ-00475

Copy Product Info

Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$112	2-4 weeks	2-4 weeks
10 μg	$183	2-4 weeks	2-4 weeks
20 μg	$292	2-4 weeks	2-4 weeks
50 μg	$545	2-4 weeks	2-4 weeks
100 μg	$792	2-4 weeks	2-4 weeks
200 μg	$1,150	2-4 weeks	2-4 weeks
500 μg	$1,900	2-4 weeks	2-4 weeks
1 mg	$2,730	2-4 weeks	2-4 weeks

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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	AAH05313.1
Synonyms	Tissue Kallikrein,KLK1,Kidney/Pancreas/Salivary Gland Kallikrein,Kallikrein-1
Amino Acid	Pro19-Ser262
Construction	Pro19-Ser262
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	38-55 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 2 mM CaCl<sub>2</sub>, pH 8.0.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.