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Anti-CD10 Antibody-PE (4G105) is a PE-conjugated Mouse antibody targeting CD10. Anti-CD10 Antibody-PE (4G105) can be used in FCM.
Description | Anti-CD10 Antibody-PE (4G105) is a PE-conjugated Mouse antibody targeting CD10. Anti-CD10 Antibody-PE (4G105) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG2a |
Clone | 4G105 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human MME(CD10) expression in Daudi cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD10 / Neprilysin / MME (rh CD10 / Neprilysin / MME; TMPY-02315; NP_000893.2; Tyr52-Trp750) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. The cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had the function to degrade some small secreted peptides such as the amyloid beta-peptide. It exists as a membrane-bound protein and has a high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes. |
Conjucates | PE |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Human CD10 / Neprilysin / MME protein (TMPY-02315) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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