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Anti-Orexin A Polyclonal Antibody is a Rabbit antibody targeting Orexin A. Anti-Orexin A Polyclonal Antibody can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
| Description | Anti-Orexin A Polyclonal Antibody is a Rabbit antibody targeting Orexin A. Anti-Orexin A Polyclonal Antibody can be used in ELISA,WB. |
| Synonyms | PREPROOREXIN, PPOX, PPORX, OX, ORX-A, orexin-A, OrexinA, Orexin precursor, Orexin A, Orexin, OREX, Hypocretin1, Hypocretin(orexin) neuropeptide precursor, Hypocretin neuropeptide precursor, Hypocretin A, Hypocretin 1, Hypocretin, HCRT1, HCRT 1, HCRT |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Human U251 cell lysates Primary: Anti-Orexin A (TMAB-01290) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 13 kDa Observed band size: 12 kDa ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic and Endoplasmic reticulum |
| Tissue Specificity | Abundantly expressed in subthalamic nucleus but undetectable in other brain regions tested (hypothalamus was not tested) and in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. |
| Immunogen | KLH conjugated synthetic peptide: human Orexin A |
| Antigen Species | Human |
| Gene Name | HCRT |
| Gene ID | |
| Protein Name | Orexin |
| Uniprot ID | |
| Biology Area | Obesity,Metabolism,Hormones |
| Function | Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. |
| Molecular Weight | Theoretical: 13 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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