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Anti-PARP1 Antibody (6J247) (Synonyms: PPOL, Poly-PARP, PARS, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADP...)
Catalog No. TMAC-00892 Copy Product Info
🥰Excellent
Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.
Anti-PARP1 Antibody (6J247)
Copy Product Info🥰Excellent
Catalog No. TMAC-00892
Synonyms PPOL, Poly-PARP, PARS, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT 1, ADPRT
Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.
Anti-PARP1 Antibody
(6J247)
(6J247)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB. |
| Synonyms | PPOL, Poly-PARP, PARS, PARP-1, PARP, pADPRT-1, ARTD1, ADPRT1, ADPRT 1, ADPRT |
| Clone | 6J247 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of 1) Jurkat ,2) Hela cells, using TMAC-00892 diluted at 1:2,000.  |
| Application | |
| Recommended Dose | WB: 1:1000-3000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Affinity purification using immunogen. |
| Appearance | Liquid |
| Formulation | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate. |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | Actual: 116, 89 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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