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Anti-PARP1 Antibody (6J247)

😃Good
Catalog No. TMAC-00892

Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.

Anti-PARP1 Antibody (6J247)

Anti-PARP1 Antibody (6J247)

😃Good
Catalog No. TMAC-00892
Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-3000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationAffinity purification using immunogen.
AppearanceLiquid
FormulationMouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundPoly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
Chemical Properties
Molecular WeightActual: 116, 89 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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