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Anti-PARP1 Antibody (6J247)
😃Good
Catalog No. TMAC-00892
Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.
Anti-PARP1 Antibody (6J247)
Anti-PARP1 Antibody (6J247)
😃Good
Catalog No. TMAC-00892
Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PARP1 Antibody (6J247) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (6J247) can be used in WB. |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-3000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Affinity purification using immunogen. |
| Appearance | Liquid |
| Formulation | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate. |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | Actual: 116, 89 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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