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GRIK2 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-04318
Synonyms: GLUR6, EAA4, MRT6, GLR6, glutamate receptor, ionotropic, kainate 2, GLUK6, GluK2

GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK2 has a role in the maintenance of urothelial CSCs/CICs and that GRIK2 and ALDH1 can be prognosis prediction markers for urinary tract carcinomas.

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GRIK2 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
Description GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK2 has a role in the maintenance of urothelial CSCs/CICs and that GRIK2 and ALDH1 can be prognosis prediction markers for urinary tract carcinomas.
Species Human
Expression System HEK293
Tag hFc
Accession Number Q13002-5
Synonyms GLUR6, EAA4, MRT6, GLR6, glutamate receptor, ionotropic, kainate 2, GLUK6, GluK2
Construction A DNA sequence encoding the human GRIK2 (NP_001159719.1) (Met1-Pro561) was expressed with the Fc region of human IgG1 at the C-terminus.
Protein Purity > 90 % as determined by SDS-PAGE.
Molecular Weight Approxiamtely 86.5 kDa
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK2 has a role in the maintenance of urothelial CSCs/CICs and that GRIK2 and ALDH1 can be prognosis prediction markers for urinary tract carcinomas.

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Keywords

GRIK2 Protein, Human, Recombinant (hFc) GLUR6 GLR-6 MRT-6 GLR 6 EAA 4 GLUR-6 EAA4 GLUK-6 GLUR 6 MRT6 GLR6 glutamate receptor, ionotropic, kainate 2 MRT 6 GLUK 6 EAA-4 GLUK6 GluK2 recombinant recombinant-proteins proteins protein

 

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