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Iperoxo (Synonyms: Iperoxo iodide)

Catalog No. T25538 Copy Product Info
Purity: 99.81%
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Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.

Iperoxo

Copy Product Info
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Catalog No. T25538
Synonyms Iperoxo iodide

Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.

Iperoxo
Cas No. 247079-84-1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$46In StockIn Stock
5 mg$108In StockIn Stock
10 mg$177In StockIn Stock
25 mg$357In StockIn Stock
50 mg$538In StockIn Stock
100 mg$788In StockIn Stock
200 mg$1,080-In Stock
1 mL x 10 mM (in DMSO)$119In StockIn Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.81%
Appearance:Solid
Color:White
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Product Introduction

Iperoxo AI Summary
Iperoxo shows high affinity for the muscarinic M2 receptor with a Ki value of 4.9 nM and exhibits strong agonist activity at this receptor with an EC50 value of 0.28 nM. It has an efficacy relative to carbachol of 125.0%, making it a robust activator of the muscarinic M2 receptor. However, it demonstrates lower affinity for the muscarinic M1 and M3 receptors, with Ki values of 350.0 nM and 550.0 nM, respectively..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.
SynonymsIperoxo iodide
Chemical Properties
Molecular Weight324.16
FormulaC10H17IN2O2
Cas No.247079-84-1
Smiles[I-].C[N+](C)(C)CC#CCOC1=NOCC1
Relative Density.1.31g/cm3
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 56.7 mg/mL (174.91 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0849 mL15.4245 mL30.8490 mL154.2448 mL
5 mM0.6170 mL3.0849 mL6.1698 mL30.8490 mL
10 mM0.3085 mL1.5424 mL3.0849 mL15.4245 mL
20 mM0.1542 mL0.7712 mL1.5424 mL7.7122 mL
50 mM0.0617 mL0.3085 mL0.6170 mL3.0849 mL
100 mM0.0308 mL0.1542 mL0.3085 mL1.5424 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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