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Anti-Phospho-H2AFX (S139) Antibody (2B111)

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Catalog No. TMAC-03223

Anti-Phospho-H2AFX (S139) Antibody (2B111) is a Rabbit antibody targeting Phospho-H2AFX (S139). Anti-Phospho-H2AFX (S139) Antibody (2B111) can be used in WB,IHC,ICC/IF,IP.

Anti-Phospho-H2AFX (S139) Antibody (2B111)

Anti-Phospho-H2AFX (S139) Antibody (2B111)

😃Good
Catalog No. TMAC-03223
Anti-Phospho-H2AFX (S139) Antibody (2B111) is a Rabbit antibody targeting Phospho-H2AFX (S139). Anti-Phospho-H2AFX (S139) Antibody (2B111) can be used in WB,IHC,ICC/IF,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-H2AFX (S139) Antibody (2B111) is a Rabbit antibody targeting Phospho-H2AFX (S139). Anti-Phospho-H2AFX (S139) Antibody (2B111) can be used in WB,IHC,ICC/IF,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:100-200; ICC/IF: 1:50-200; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundHistone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and maps to chromosome 9 and 11q23, respectively. H2A.X differs from the other members of the H2A family by the presence of a highly conserved C-terminal motif. It is rapidly phosphorylated in response to ionizing radiation and plays an important role in the recognition and repair of DNA double stranded breaks. The phosphorylated form of H2A.X, designated ?-H2A.X, forms nuclear foci at the heavy chain constant region of cells involved in class switch recombination (CSR), a region-specific DNA reaction that replaces one immunoglobulin heavy chain constant region gene with another. The phosphorylated ?-H2A.X is also thought to initiate subsequent repair factors, including Rad50, Rad51 and BRCA1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Histone H2A.X around the phosphorylation site of Ser139
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 15 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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