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Anti-Phospho-H2AFX (S139) Antibody (2B111)
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Catalog No. TMAC-03223
Anti-Phospho-H2AFX (S139) Antibody (2B111) is a Rabbit antibody targeting Phospho-H2AFX (S139). Anti-Phospho-H2AFX (S139) Antibody (2B111) can be used in WB,IHC,ICC/IF,IP.
Anti-Phospho-H2AFX (S139) Antibody (2B111)
Anti-Phospho-H2AFX (S139) Antibody (2B111)
😃Good
Catalog No. TMAC-03223
Anti-Phospho-H2AFX (S139) Antibody (2B111) is a Rabbit antibody targeting Phospho-H2AFX (S139). Anti-Phospho-H2AFX (S139) Antibody (2B111) can be used in WB,IHC,ICC/IF,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-Phospho-H2AFX (S139) Antibody (2B111) is a Rabbit antibody targeting Phospho-H2AFX (S139). Anti-Phospho-H2AFX (S139) Antibody (2B111) can be used in WB,IHC,ICC/IF,IP. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:100-200; ICC/IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Histone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and maps to chromosome 9 and 11q23, respectively. H2A.X differs from the other members of the H2A family by the presence of a highly conserved C-terminal motif. It is rapidly phosphorylated in response to ionizing radiation and plays an important role in the recognition and repair of DNA double stranded breaks. The phosphorylated form of H2A.X, designated ?-H2A.X, forms nuclear foci at the heavy chain constant region of cells involved in class switch recombination (CSR), a region-specific DNA reaction that replaces one immunoglobulin heavy chain constant region gene with another. The phosphorylated ?-H2A.X is also thought to initiate subsequent repair factors, including Rad50, Rad51 and BRCA1. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human Histone H2A.X around the phosphorylation site of Ser139 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 15 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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