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Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody

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Catalog No. TMAC-01262

Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF2S1 (Ser 52). Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody can be used in WB,IP,IF,IHC-P.

Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody

Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody

😃Good
Catalog No. TMAC-01262
Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF2S1 (Ser 52). Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody can be used in WB,IP,IF,IHC-P.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF2S1 (Ser 52). Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody can be used in WB,IP,IF,IHC-P.
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate)
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationImmunogen affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2, eIF2 and eIF2 (eukaryotic translation initiation factor 2 , and , respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2 controls the rate of tRNA translation. When eIF2 is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2 is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A short amino acid sequence containing phosphorylated Ser 52 of eIF2α of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 36 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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