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Anti-CD16/FCGR3 Polyclonal Antibody

😃Good
Catalog No. TMAB-00337
Alias Fc receptor, IgG, low affinity III, CD16

Anti-CD16/FCGR3 Polyclonal Antibody is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Polyclonal Antibody can be used in WB.

Anti-CD16/FCGR3 Polyclonal Antibody

Anti-CD16/FCGR3 Polyclonal Antibody

😃Good
Catalog No. TMAB-00337Alias Fc receptor, IgG, low affinity III, CD16
Anti-CD16/FCGR3 Polyclonal Antibody is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2207-10 days
100 μL$3737-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-CD16/FCGR3 Polyclonal Antibody is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Polyclonal Antibody can be used in WB.
AliasFc receptor, IgG, low affinity III, CD16
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Sample:
Raw264.7 (Mouse) Cell Lysate at 30 μg
Primary: Anti-CD16 (TMAB-00337) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kDa
Observed band size: 50 kDa
2. Sample:
Lane 1: Thymus (Rat) Lysate at 40 μg
Lane 2: LympHnode (Mouse) Lysate at 40 μg
Primary: Anti-CD16 (TMAB-00337) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 60 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Secreted. Exists also as a soluble receptor.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IGFR3/CD16
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
NK Cells,Human Lineage Negative,NK Cell Lineage,Monocytic Lineage,Neutrophil Lineage
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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