Shopping Cart

Your shopping cart is currently empty

Dipivefrin hydrochloride

Name: Dipivefrin hydrochloride
Brand: TargetMol
SKU: T0103
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. T0103Cas No. 64019-93-8

Alias Dipivefrin HCL

Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.

Dipivefrin hydrochloride

Copy Product Info

🥰Excellent

Purity: 99.96%

Catalog No. T0103Alias Dipivefrin HCLCas No. 64019-93-8

Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$48	In Stock	In Stock
50 mg	$77	In Stock	In Stock
100 mg	$118	In Stock	In Stock
200 mg	$178	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.96%

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Dipivefrin hydrochloride AI Summary

Dipivefrin hydrochloride exhibits bioactivity across a diverse range of biological assays with varying potencies: 1. Inhibits AmpC Beta-Lactamase with a potency of 2818.4 nM. 2. Acts as a beta-arrestin-biased ligand for the beta2-adrenergic receptor with potencies of 1458.1 nM and 259.3 nM in different assays. 3. Possesses delayed death inhibitory activity against the malarial parasite plastid with potencies of 18526.0 nM (96-hour incubation) and 11689.1 nM (48-hour incubation). 4. Inhibits Polymerase Iota with a potency of 89125.1 nM. 5. Shows inhibitory activity against TGF-b in a cytotoxic counterscreen assay with a potency of 12589.3 nM. 6. Functions as a Beta-2AR agonist with an EC50 of 7130.0 nM via the FAP method. 7. Inhibits Hepatitis C Virus (HCV) with a potency of 501.2 nM. 8. Acts as an inverse agonist for the GLP-1 receptor with a potency of 3981.1 nM. 9. Inhibits human tyrosyl-DNA phosphodiesterase 1 (TDP1) with identical potencies of 9034.9 nM both in the presence and absence of CPT. 10. Inhibits PTHR with a potency of 1995.3 nM. 11. Validated as a GLP-1 receptor agonist with potencies of 69.9 nM and 82.0 nM in different validation assays. Additionally, Dipivefrin hydrochloride exhibits slight inhibition of cell viability in Vero E6 cells infected with SARS-CoV-2, with an inhibition index of 1.01 in comparison to the arbidol control, suggesting some potential antiviral activity although the overall effect is relatively modest. These results collectively indicate that Dipivefrin hydrochloride has potential multifaceted pharmacological properties..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.
Synonyms	Dipivefrin HCL

Chemical Properties

Molecular Weight	387.9
Formula	C₁₉H₂₇NO₅·HCl
Cas No.	64019-93-8
Smiles	Cl.CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (128.9 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.16 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5780 mL	12.8899 mL	25.7798 mL	128.8992 mL
5 mM	0.5156 mL	2.5780 mL	5.1560 mL	25.7798 mL
10 mM	0.2578 mL	1.2890 mL	2.5780 mL	12.8899 mL
20 mM	0.1289 mL	0.6445 mL	1.2890 mL	6.4450 mL
50 mM	0.0516 mL	0.2578 mL	0.5156 mL	2.5780 mL
100 mM	0.0258 mL	0.1289 mL	0.2578 mL	1.2890 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc