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Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (2M987) is a Rabbit antibody targeting Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III). Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (2M987) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $94 | 7-10 days | 7-10 days | |
| 100 μL | $292 | 7-10 days | 7-10 days |
| Description | Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (2M987) is a Rabbit antibody targeting Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III). Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (2M987) can be used in WB. |
| Ig Type | Rabbit IgG |
| Clone | 2M987 |
| Specificity | Zika virus (strain Zika SPH2015) E / Envelope protein (Domain III) |
| Verified Activity | Anti-Zika virus (strain Zika SPH2015) E / Envelope protein (Domain III) rabbit monoclonal antibody at 1:2000 dilution -Sample:Zika virus (strain Zika SPH2015) E / Envelope protein (Domain III,His Tag ) -Lane A: 5ng -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
| Application | |
| Recommended Dose | WB: 1:2000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Zika virus (strain Zika SPH2015) E / Envelope protein (Domain III) ( TMPY-04895; ALU33341.1; Val593-Lys699). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF.Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Zika virus (strain Zika SPH2015) E / Envelope protein (Domain III) Protein (TMPY-04895) |
| Antigen Species | ZIKV |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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