Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-L1CAM Antibody-APC (5I245)
🥰Excellent
Catalog No. TMAY-00333A
Anti-L1CAM Antibody-APC (5I245) is a APC-conjugated Mouse antibody targeting L1CAM. Anti-L1CAM Antibody-APC (5I245) can be used in FCM.
Anti-L1CAM Antibody-APC (5I245)
Anti-L1CAM Antibody-APC (5I245)
🥰Excellent
Catalog No. TMAY-00333A
Anti-L1CAM Antibody-APC (5I245) is a APC-conjugated Mouse antibody targeting L1CAM. Anti-L1CAM Antibody-APC (5I245) can be used in FCM.
Product information is being updated, if you want to purchase, please click the bulk custom button.
Bulk & Custom
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-L1CAM Antibody-APC (5I245) is a APC-conjugated Mouse antibody targeting L1CAM. Anti-L1CAM Antibody-APC (5I245) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 5I245 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human L1CAM expression on Hela cells. Cells were stained with APC-conjugated anti-Human L1CAM. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD171 / N-CAML1 / L1CAM (rh CD171 / N-CAML1 / L1CAM; TMPY-01431; NP_000416.1; Met1-Glu1120) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif in the sixth Ig domain of L1CAM is a binding site for integrins, thus important for nuclear signaling. Disruption of L1CAM function causes three X-linked neurological syndromes, i.e. hydrocephalus, MASA syndrome (mental retardation, aphasia, shuffling gait, and adducted thumbs), and spastic paraplegia syndrome. Overexpression of L1CAM in normal and cancer cells increased motility, enhanced growth rate, and promoted cell transformation and tumorigenicity. Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy. |
| Conjucates | APC |
| Others Formats | Unconjugated/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human CD171 / N-CAML1 / L1CAM protein (TMPY-01431) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-L1CAM Antibody-APC (5I245) | purchase Anti-L1CAM Antibody-APC (5I245) | Anti-L1CAM Antibody-APC (5I245) cost | order Anti-L1CAM Antibody-APC (5I245)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.