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Anti-COMP Antibody (8Z374)
😃Good
Catalog No. TMAY-00401
Alias THBS5, PSACH, MED, EPD1, EDM1, cartilage oligomeric matrix protein
Anti-COMP Antibody (8Z374) is a Mouse antibody targeting COMP. Anti-COMP Antibody (8Z374) can be used in ELISA(Cap).
Anti-COMP Antibody (8Z374)
Anti-COMP Antibody (8Z374)
😃Good
Catalog No. TMAY-00401Alias THBS5, PSACH, MED, EPD1, EDM1, cartilage oligomeric matrix protein
Anti-COMP Antibody (8Z374) is a Mouse antibody targeting COMP. Anti-COMP Antibody (8Z374) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA(Cap) Reactivity: Human |
| Alias | THBS5, PSACH, MED, EPD1, EDM1, cartilage oligomeric matrix protein |
| Ig Type | Mouse IgG1 |
| Clone | 8Z374 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human COMP (rh COMP; TMPY-00725; NP_000086.2; Met1-Ala757). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein is expressed primarily in cartilage, ligament, and tendon, and binds to other ECM proteins such as collagen I, II and IX with high affinities depending on the divalent cations Zn2+ or Ni2+. COMP is a secreted glycoprotein that is important for growth plate organization and function. It is suggested to play a role in cell growth and development, and recent studies have revealed the possible mechanism that it protects cells against death by elevating members of the IAP (inhibitor of apoptosis protein) family of survival proteins. Mutations in COMP cause two skeletal dysplasias, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (EDM1), and up-regulated expression of COMP are observed in rheumatoid arthritis and certain carcinomas. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human COMP Protein (TMPY-00725) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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