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Anthraflavic acid
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Catalog No. T5941Cas No. 84-60-6
Alias 2,6-Dihydroxyanthraquinone
Anthraflavic acid (2,6-Dihydroxyanthraquinone), a flavonoid, is a potent IQ mutagenicity and cytochrome P-448 inhibitor.
Anthraflavic acid
🥰Excellent
Purity: 98.37%
Catalog No. T5941Alias 2,6-DihydroxyanthraquinoneCas No. 84-60-6
Anthraflavic acid (2,6-Dihydroxyanthraquinone), a flavonoid, is a potent IQ mutagenicity and cytochrome P-448 inhibitor.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $29 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $44 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.37%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Anthraflavic acid (2,6-Dihydroxyanthraquinone), a flavonoid, is a potent IQ mutagenicity and cytochrome P-448 inhibitor. |
| In vitro | Anthraflavic acid is a potent inhibitor of IQ mutagenicity by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways. |
| Kinase Assay | The metabolic activation of IQ to mutagens was determined using the Ames mutagenicity test ?and employing Salmonella lyphimurium strain TA98 ?and 10% hepatic preparations as activation systems.?IQ and anthraflavic acid were dissolved in DMSO so that the solvent levels never exceeded 100 μl?per phile.?In experiments where microsomes onl~ were used as the activation system, $9 mix was supplemented with 1 unit/plate of glucose-6-phosphate dehydrogenase.?Pre-incubation conditions are described in the appropriate legends. |
| Synonyms | 2,6-Dihydroxyanthraquinone |
| Molecular Weight | 240.21 |
| Formula | C14H8O4 |
| Cas No. | 84-60-6 |
| Smiles | OC1=CC2=C(C=C1)C(=O)C1=CC(O)=CC=C1C2=O |
| Relative Density. | 1.3032 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 5.5 mg/mL (22.9 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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