MDL-1/CLEC5A Protein, Human, Recombinant (hFc)

Catalog No. TMPK-01205

MDL-1/CLEC5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q9NY25-1.

MDL-1/CLEC5A Protein, Human, Recombinant (hFc)

Catalog No. TMPK-01205

MDL-1/CLEC5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q9NY25-1.

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$56	-	In Stock
10 μg	$88	-	In Stock
20 μg	$143	-	In Stock
50 μg	$278	7-10 days	7-10 days
100 μg	$465	-	In Stock
200 μg	$839	7-10 days	7-10 days
500 μg	$1,850	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Information

Biological Activity	Immobilized Human MDL-1, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-MDL-1 Antibody, hFc Tag with the EC50 of 17.4ng/ml determined by ELISA.
Description	MDL-1/CLEC5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q9NY25-1.
Species	Human
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	Q9NY25-1
Synonyms	MDL-1,MDL1,DAP12-associating lectin 1,CLECSF5,CLEC5A
Construction	Tyr26-Lys188
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	46 kDa (predicted). Due to glycosylation, the protein migrates to 63-70 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.