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Anti-ENPP7 Antibody (6F951)

😃Good
Catalog No. TMAY-01284
Alias Gm254, ectonucleotide pyrophosphatase/phosphodiesterase 7, Alk-SMase

Anti-ENPP7 Antibody (6F951) is a Mouse antibody targeting ENPP7. Anti-ENPP7 Antibody (6F951) can be used in ELISA.

Anti-ENPP7 Antibody (6F951)

Anti-ENPP7 Antibody (6F951)

😃Good
Catalog No. TMAY-01284Alias Gm254, ectonucleotide pyrophosphatase/phosphodiesterase 7, Alk-SMase
Anti-ENPP7 Antibody (6F951) is a Mouse antibody targeting ENPP7. Anti-ENPP7 Antibody (6F951) can be used in ELISA.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-ENPP7 Antibody (6F951) is a Mouse antibody targeting ENPP7. Anti-ENPP7 Antibody (6F951) can be used in ELISA.
AliasGm254, ectonucleotide pyrophosphatase/phosphodiesterase 7, Alk-SMase
Ig Type
Monoclonal Mouse IgG1
Clone
6F951
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ENPP7 / NPP-7 (rh ENPP7; TMPY-01070; NP_848638.2; Met 1-Ser 439). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundEctonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I membrane protein which belongs to thenucleotide pyrophosphatase / phosphodiesterase family. ENPP7 / NPP-7 is expressed in the intestines and human bile. ENPP7 / NPP-7 is localized at the surface of the microvillar membrane in small intestine enterocytes, as well as in endosome-like structures and in Golgi complex. The main function of ENPP7 / NPP-7 is to convert the dietary sphingomyelin into ceramide, the sphingolipid messengers via hydrolyzation. ENPP7 / NPP-7 is also reported to exert a phospholipase C activity toward palmitoyl lyso-phosphocholine. The activity of this enzyme is inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Further, It has been shown in studies that decreased levels of ENPP7 / NPP-7 may be associated with human colon cancer.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human ENPP7 protein ( Catalog#10885-H08H)
Antigen Species
Human
Biology Area
Phosphatases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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