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Divaplon

Divaplon
Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that exhibits non-sedating anxiolytic properties in a rat model of anxiety.
Catalog No. T27186Cas No. 90808-12-1
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Purity:97.49%
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Divaplon

Purity: 97.49%
Catalog No. T27186Alias RU-32698, RU32698, RU 32698Cas No. 90808-12-1

Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that exhibits non-sedating anxiolytic properties in a rat model of anxiety.
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Pack SizePriceAvailabilityQuantity
1 mg$146In Stock
5 mg$350In Stock
10 mg$530In Stock
25 mg$859In Stock
50 mg$1,180In Stock
100 mg$1,590In Stock
500 mg$3,190In Stock
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Product Introduction

Bioactivity
Description
Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that exhibits non-sedating anxiolytic properties in a rat model of anxiety.
In vivo
Divaplon (1-60 mg/kg; injection; mice) clearly produced effects on the acquisition of conditioned fear. As the drug has been shown to produce anticonvulsant and anxiolytic-like effects without sedation or depression of motor activity. The results show that BZ (omega) receptor partial agonists without apparent sedative actions can disrupt fear learning, indicating that the effects of this class of drugs on passive avoidance learning can be dissociated from sedation.[4]
AliasRU-32698, RU32698, RU 32698
Chemical Properties
Molecular Weight295.34
FormulaC17H17N3O2
Cas No.90808-12-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (169.3 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3859 mL16.9296 mL33.8593 mL169.2964 mL
5 mM0.6772 mL3.3859 mL6.7719 mL33.8593 mL
10 mM0.3386 mL1.6930 mL3.3859 mL16.9296 mL
20 mM0.1693 mL0.8465 mL1.6930 mL8.4648 mL
50 mM0.0677 mL0.3386 mL0.6772 mL3.3859 mL
100 mM0.0339 mL0.1693 mL0.3386 mL1.6930 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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