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GPC3 targeting peptide 1

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Catalog No. TP3051Cas No. 3066113-41-2

GPC3 targeting peptide 1 is a synthetic peptide ligand that binds to glypican-3 (GPC3) with a high affinity dissociation constant (Kd) of 0.23 nM. GPC3 targeting peptide 1 serves as a precise molecular probe for detecting and targeting GPC3-expressing tumor cells, particularly in hepatocellular carcinoma research, facilitating targeted imaging and therapeutic applications.

GPC3 targeting peptide 1
Other Forms of GPC3 targeting peptide 1:
GPC3 targeting peptide 1 TFATP3744
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GPC3 targeting peptide 1

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Catalog No. TP3051Cas No. 3066113-41-2
GPC3 targeting peptide 1 is a synthetic peptide ligand that binds to glypican-3 (GPC3) with a high affinity dissociation constant (Kd) of 0.23 nM. GPC3 targeting peptide 1 serves as a precise molecular probe for detecting and targeting GPC3-expressing tumor cells, particularly in hepatocellular carcinoma research, facilitating targeted imaging and therapeutic applications.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$6087-10 days7-10 days
5 mg$1,5187-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
GPC3 targeting peptide 1 is a synthetic peptide ligand that binds to glypican-3 (GPC3) with a high affinity dissociation constant (Kd) of 0.23 nM. GPC3 targeting peptide 1 serves as a precise molecular probe for detecting and targeting GPC3-expressing tumor cells, particularly in hepatocellular carcinoma research, facilitating targeted imaging and therapeutic applications.
Targets&IC50
GPC3:0.23 nM (Kd)
Chemical Properties
Molecular Weight1777.05
FormulaC89H117N17O20S
Cas No.3066113-41-2
SmilesC(C1=CC2=C(C=C1)C=CN=C2)[C@@H]3N(C)C(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CC5=CC=C(C(O)=O)C=C5)NC(=O)[C@H](CCC(N)=O)N(C)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCOC)N(C)C(=O)[C@H](CCCCN)N(C)C(=O)CSC[C@@H](C(N)=O)N(C)C(=O)[C@H](CC=6C=CC(=NC6)C7=CC=CC=C7)NC(=O)CNC3=O)[H])[H]
Sequencecyclo(Ac-MeLys--MeHseMe-Asp-MeGln-F4COO-Ile-Ile-Tyr-MeNal27N-Gly-3Py6Ph-MeCys)-NH2
Sequence Shortcyclo(Ac-MeK--MeHseMe-D-MeQ-F4COO-I-I-Y-MeNal27N-G-3Py6Ph-MeC)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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