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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $534 | 7-10 days | |
500 μg | $2,140 | 7-10 days | |
1 mg | $3,570 | 7-10 days |
Biological Information | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Description | As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. |
Species | Cynomolgus |
Expression System | HEK293 Cells |
Tag | N-His |
Accession Number | Q68VD0-1 |
Synonyms | NKG2C,NK cell receptor C,CD159c,KLRC2 |
Construction | Ile94-Leu231 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | 16.9 kDa (predicted). Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. |
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