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Anti-VSIG4 Antibody (8P101)
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Catalog No. TMAY-02260
Alias Z39IG, V-set and immunoglobulin domain containing 4, CRIg
Anti-VSIG4 Antibody (8P101) is a Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody (8P101) can be used in ELISA(Cap).
Anti-VSIG4 Antibody (8P101)
Anti-VSIG4 Antibody (8P101)
😃Good
Catalog No. TMAY-02260Alias Z39IG, V-set and immunoglobulin domain containing 4, CRIg
Anti-VSIG4 Antibody (8P101) is a Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody (8P101) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA(Cap) Reactivity: Human |
| Alias | Z39IG, V-set and immunoglobulin domain containing 4, CRIg |
| Ig Type | Rabbit IgG |
| Clone | 8P101 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human VSIG4 (rh VSIG4; TMPY-01907; Q9Y279-1; Met1-Pro283). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. No VSIG4 expression appears to be present in T and B cells. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. Mouse VSIG4 is synthesized as a 28 amino acid precursor that contains a signal sequence, a V-type I g domain (aa 36-115), one potential N-linked glycosylation site, and a single transmembrane domain. The V-type I g domain of mouse VSIG4 shares 86% and 8% aa sequence identity with the V-type I g domains of rat and human VSIG4, respectively. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human VSIG4 Protein (TMPY-01907) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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