TGF alpha Protein, Human, Recombinant (CHO)

Name: TGF alpha Protein, Human, Recombinant (CHO)
Brand: TargetMol
SKU: TMPS-00132
Rating: 4.5 (1 reviews)

(Synonyms: Transforming Growth Factor-α, TGFα, TGF-type I, Sacroma growth factor, ETGF) Copy Product Info

Synonyms: Transforming Growth Factor-α, TGFα, TGF-type I, Sacroma growth factor, ETGF

Catalog No. TMPS-00132 Copy Product Info

TGF alpha Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is P01135.

Pack Size	Price	USA Stock	Global Stock
5 µg	$57	7-10 days	7-10 days
10 µg	$76	7-10 days	7-10 days
25 µg	$113	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC

Appearance:Solid

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 0.4 ng/ml, measured in a cell proliferation assay using 3T3 cells.
Description	TGF alpha Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is P01135.
Species	Human
Expression System	CHO Cells
Tag	Tag Free
Accession Number	P01135
Construction	Val40-Ala89
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Transforming Growth Factor-α, TGFα, TGF-type I, Sacroma growth factor, ETGF
Research Background	Protransforming Growth Factor-alpha (TGF-alpha), also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. ProTGF-alpha signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. It may function as either a membrane-bound ligand or a soluble ligand. Membrane-bound proTGF-alpha plays a role in cell-cell adhesion and juxtacrine stimulation of adjacent cells. The soluble form of the cytokine is released from the membrane-bound form by proteolytic cleavage and acts as a mitogen for cell proliferation.

Chemical Properties

Molecular Weight

8~10 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.