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Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody (Synonyms: Protein kinase C zeta, Protein kinase C gamma, Prot...)
Catalog No. TMAC-03307 Copy Product Info
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Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Thr198). Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody can be used in IF,IP,WB.
Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-03307
Synonyms Protein kinase C zeta, Protein kinase C gamma, Protein kinase C epsilon, Protein kinase C delta, Protein kinase C beta, Protein kinase C alpha, Protein kinase C, PRKCZ, PRKCG, PRKCE, PRKCD, PRKCB2, PRKCB1, PRKCB, PRKCA (p-Thr198), PRKCA (p-T198), PRKCA, p-PRKCA (Thr198), p-PRKCA (T198), PKCG, PKCE, PKCD, PKCB, PKC-alpha, PKC-A, PKCA, PKC2, PKC zeta, PKC gamma, PKC epsilon, PKC delta, PKC beta, PKC alpha, Phospho-PRKCA (T198), KPCA_HUMAN
Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Thr198). Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody can be used in IF,IP,WB.
Anti-Phospho-PRKCA
(Thr198) Polyclonal Antibody
(Thr198) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Thr198). Anti-Phospho-PRKCA (Thr198) Polyclonal Antibody can be used in IF,IP,WB. |
| Synonyms | Protein kinase C zeta, Protein kinase C gamma, Protein kinase C epsilon, Protein kinase C delta, Protein kinase C beta, Protein kinase C alpha, Protein kinase C, PRKCZ, PRKCG, PRKCE, PRKCD, PRKCB2, PRKCB1, PRKCB, PRKCA (p-Thr198), PRKCA (p-T198), PRKCA, p-PRKCA (Thr198), p-PRKCA (T198), PKCG, PKCE, PKCD, PKCB, PKC-alpha, PKC-A, PKCA, PKC2, PKC zeta, PKC gamma, PKC epsilon, PKC delta, PKC beta, PKC alpha, Phospho-PRKCA (T198), KPCA_HUMAN |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PKAα cat phosphorylation in non-transfected (A) and human PKAα cat transfected (B) 293T whole cell lysates. 2. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.   |
| Application | |
| Recommended Dose | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Immunogen affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified, designated Cα, Cβ and Cγ, that each represent specific gene products. Cα and Cβ are closely related (93% amino acid sequence similarity), whereas Cγ displays 83% and 79% similarity to Cα and Cβ, respectively. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus where it phosphorylates the transcription factor cAMP response element binding protein (CREB) on Serine 133, which in turn leads to TFIIB binding to TATA-box-binding protein TBP1, thus linking phospho-CREB to the Pol II transcription initiation complex. The phosphorylation at Threonine 198 is cAMP dependent. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A short amino acid sequence containing Thr 198 phosphorylated PKAα cat of human origin |
| Antigen Species | human |
| Molecular Weight | Theoretical: PKAα cat: 40, PKAβ cat: 53, PKAγ cat: 39-40 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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