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Anti-CD58 Antibody-PE (8M86)
🥰Excellent
Catalog No. TMAY-02332P
Anti-CD58 Antibody-PE (8M86) is a PE-conjugated Mouse antibody targeting CD58. Anti-CD58 Antibody-PE (8M86) can be used in FCM.
Anti-CD58 Antibody-PE (8M86)
Anti-CD58 Antibody-PE (8M86)
🥰Excellent
Catalog No. TMAY-02332P
Anti-CD58 Antibody-PE (8M86) is a PE-conjugated Mouse antibody targeting CD58. Anti-CD58 Antibody-PE (8M86) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD58 Antibody-PE (8M86) is a PE-conjugated Mouse antibody targeting CD58. Anti-CD58 Antibody-PE (8M86) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8M86 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD58 expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD58. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LFA-3 / CD58 (rh LFA-3 / CD58; TMPY-03489; AAH05930.1; Met1-Arg215) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/PerCP/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human LFA-3 / CD58 Protein (TMPY-03489) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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