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EFNA1 Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00546
Synonyms: TNFAIP4, LERK1, Tumor Necrosis Factor α-Induced Protein 4, Immediate Early Response Protein B61, Ephrin-A1, EPH-Related Receptor Tyrosine Kinase Ligand 1, TNF Alpha-Induced Protein 4, EFNA1, EPLG1, TNF α-Induced Protein 4, Tumor Necrosis Factor Alpha-Induced Protein 4, LERK-1

Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
EFNA1 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.
Species Human
Expression System Human Cells
Tag C-Fc
Accession Number AAH32698.1
Synonyms TNFAIP4, LERK1, Tumor Necrosis Factor α-Induced Protein 4, Immediate Early Response Protein B61, Ephrin-A1, EPH-Related Receptor Tyrosine Kinase Ligand 1, TNF Alpha-Induced Protein 4, EFNA1, EPLG1, TNF α-Induced Protein 4, Tumor Necrosis Factor Alpha-Induced Protein 4, LERK-1
Amino Acid Asp19-Ser182
Construction Recombinant Human Ephrin-A1 is produced by our Mammalian expression system and the target gene encoding Asp19-Ser182 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 55-60 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.

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Keywords

EFNA1 Protein, Human, Recombinant (hFc) TNFAIP4 LERK1 LERK 1 EPLG 1 TNFAIP-4 Tumor Necrosis Factor a-Induced Protein 4 Tumor Necrosis Factor α-Induced Protein 4 Immediate Early Response Protein B61 TNFAIP 4 Ephrin-A1 EPH-Related Receptor Tyrosine Kinase Ligand 1 TNF Alpha-Induced Protein 4 EFNA1 EPLG1 EPLG-1 EFNA 1 TNF α-Induced Protein 4 TNF a-Induced Protein 4 Tumor Necrosis Factor Alpha-Induced Protein 4 EFNA-1 LERK-1 recombinant recombinant-proteins proteins protein

 

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