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Methylamino-PEG2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules [PROTACs]. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $32 | 5 days | |
5 mg | $48 | 5 days | |
10 mg | $70 | 5 days | |
25 mg | $113 | 5 days | |
50 mg | $168 | 5 days | |
100 mg | $268 | 5 days |
Description | Methylamino-PEG2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules [PROTACs]. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs induce selective degradation of target proteins[1]. |
Alias | Methylamino-PEG2-t-butyl ester |
Molecular Weight | 247.33 |
Formula | C12H25NO4 |
Cas No. | 1807521-04-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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