PDGF-BB Protein, Mouse, Recombinant

Name: PDGF-BB Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00116
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis) Copy Product Info

Synonyms: SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis

Catalog No. TMPS-00116 Copy Product Info

PDGF-BB Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P31240.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$98	-	In Stock
10 µg	$170	-	In Stock
20 µg	$248	-	In Stock
50 µg	$423	-	In Stock
100 µg	$682	7-10 days	7-10 days
200 µg	$1,080	7-10 days	7-10 days
500 µg	$1,980	7-10 days	7-10 days
1 mg	$3,390	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:> 95% as analyzed by SDS-PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 2.5 ng/ml, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 4.0 × 10 5 units/mg.
Description	PDGF-BB Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P31240.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	P31240
Construction	Ser82-Thr190
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized after extensive dialysis against 10 mM sodium citrate, pH 3.0.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis
Research Background	Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In vivo, PDGF-BB is mainly produced in heart and placenta, and predominantly expressed by osteoblasts, fibroblasts, smooth muscle cells, and glial cells. An inactive precursor of PDGF-BB is produced in the endoplasmic reticulum and then activated by a proprotein convertase after secretion. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. Therefore, PDGF-BB and its related pathways are potential pharmacological targets.

Chemical Properties

Molecular Weight

~24.7 kDa (Non-reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.