Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-05381941 is a potent dual inhibitor of TAK1/p38α, with IC50s of 156 and186 nM, respectively[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 877.00 | |
50 mg | 6-8 weeks | $ 1,140.00 | |
100 mg | 6-8 weeks | $ 1,820.00 |
Description | PF-05381941 is a potent dual inhibitor of TAK1/p38α, with IC50s of 156 and186 nM, respectively[1]. |
Targets&IC50 | TAK1:156 nM (IC50), p38α:186 nM (IC50) |
In vitro | PF-05381941 inhibits LPS-stimulated release of TNF-αfrom human peripheralmononuclear (PMN) cells with an IC50 of 8 nM[1]. |
Molecular Weight | 466.53 |
Formula | C27H26N6O2 |
CAS No. | 1474022-02-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (214.35 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PF-05381941 1474022-02-0 PF 05381941 PF05381941 inhibitor inhibit