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Muscle homing peptide M12 preferentially binds to proteins on the surface of muscle cells. It enhances the cellular uptake of nanoparticles (NPs) in myoblasts. Additionally, Muscle homing peptide M12 is covalently attached to PLGA-PEG nanoparticles through an N-hydroxysuccinimide ester reaction, with the bonding occurring at the α-amino group at the N-terminus of the peptide chain.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Muscle homing peptide M12 preferentially binds to proteins on the surface of muscle cells. It enhances the cellular uptake of nanoparticles (NPs) in myoblasts. Additionally, Muscle homing peptide M12 is covalently attached to PLGA-PEG nanoparticles through an N-hydroxysuccinimide ester reaction, with the bonding occurring at the α-amino group at the N-terminus of the peptide chain. |
| Molecular Weight | 1417.58 |
| Formula | C59H100N24O17 |
| Cas No. | 2896181-32-9 |
| Smiles | C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCC1)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(O)=O)CCC3)CC4=CN=CN4)=O)CO)=O)CO)=O)[C@H](CC)C)=O)CO)=O)CCCNC(=N)N)=O)CCC2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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