Anti-TLR4 Polyclonal Antibody

Name: Anti-TLR4 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-01855
Rating: 4.5 (1 reviews)

(Synonyms: toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10) Copy Product Info

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Synonyms: toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10

Catalog No. TMAB-01855 Copy Product Info

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Anti-TLR4 Polyclonal Antibody is a Rabbit antibody targeting TLR4. Anti-TLR4 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.

Anti-TLR4 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$222	7-10 days	7-10 days
100 μL	$372	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-TLR4 Polyclonal Antibody is a Rabbit antibody targeting TLR4. Anti-TLR4 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Synonyms	toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10
Ig Type	IgG
Reactivity	Human,Rat (predicted:Mouse,Dog,Pig,Cow,Sheep)

Application	FCM ICC/IF IF IHC-Fr IHC-P WB
Recommended Dose	FCM=2 μg/Test; ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	The Toll-like receptor 4 by activating natural immunity, specific immune response involved in the start-up, Toll-like receptor 4 as an important signal transduction transmembrane receptor involved in the toxin-induced inflammation in the pathological process, its mechanisms of control On a growing concern. all regions were either double-stranded or sequenced with an alternatechemistry or covered by high quality data(i.e., phred quality >=30); an attempt was made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by at least one subclone; and the assembly was confirmed by restriction digest, except on the rare occasion of the clone being a YAC. The following abbreviations are used to associate primary accession numbers given in the feature table with their source databases: Em:, EMBL; Sw:, SWISSPROT; Tr:, TREMBL; Wp:, WORMPEP; Information on the WORMPEP database can be found at. TLR-4 plays an important role in microvascular leakage and leukocyte adhesion under the inflammatory condition associated with nonseptic thermal injury.

Antigen Details

Immunogen	KLH conjugated synthetic peptide: rat TLR4
Antigen Species	Rat
Gene Name	TLR4
Gene ID	29260
Protein Name	Toll-like receptor 4
Uniprot ID	Q9QX05
Biology Area	Inflammatory mediators,Regulatory T Cells,Receptors,Macrophage / Inflamm.,TLR Signaling,Host Virus Interaction
Function	Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.