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Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His)

(Synonyms: Nucleoprotein, Nucleocapsid protein (NP;Protein N), NP) Copy Product Info

Synonyms: Nucleoprotein, Nucleocapsid protein (NP;Protein N), NP

Catalog No. TMPH-02453 Copy Product Info
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is B8PZP3.
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His)
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$17620 days20 days
10 µg$29220 days20 days
20 µg$48920 days20 days
50 µg$92320 days20 days
100 µg$1,50020 days20 days
200 µg$1,89020 days20 days
500 µg$2,58020 days20 days
1 mg$3,26020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is B8PZP3.
Species
MeV
Expression System
Baculovirus Insect Cells
TagN-10xHis
Accession NumberB8PZP3
Amino AcidMATLLRSLALFKRNKDKPPITSGSGGAIRGIKHIIIVPIPGDSSITTRSRLLDRLVRLIGNPDVSGPKLTGALIGILSLFVESPGQLIQRITDDPDVSIRLLEVVQSDQSQSGLTFASRGTNMEDEADQYFSHDDPISSDQSRFGWFGNKEISDIEVQDPEGFNMILGTILAQIWVLLAKAVTAPDTAADSELRRWIKYTQQRRVVGEFRLERKWLDVVRNRIAEDLSLRRFMVALILDIKRTPGNKPRIAEMICDIDTYIVEAGLASFILTIKFGIETMYPALGLHEFAGELSTLESLMNLYQQMGETAPYMVILENSIQNKFSAGSYPLLWSYAMGVGVELENSMGGLNFGRSYFDPAYFRLGQEMVRRSAGKVSSTLASELGITAEDARLVSEIAMH
Construction1-400 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsNucleoprotein, Nucleocapsid protein (NP;Protein N), NP
Research Background
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure with either 12.35 or 11.64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response. Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest.
Chemical Properties
Molecular Weight46.9 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) chemical structure | Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) molecular weight