Opipramol dihydrochloride

Name: Opipramol dihydrochloride
Brand: TargetMol
SKU: T204660
Rating: 4.5 (1 reviews)

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Catalog No. T204660Cas No. 909-39-7

Alias Opipramol dihydrochloride, G-33040 dihydrochloride, Ensidon dihydrochloride

Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).

Opipramol dihydrochloride

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Catalog No. T204660Alias Opipramol dihydrochloride, G-33040 dihydrochloride, Ensidon dihydrochlorideCas No. 909-39-7

Pack Size	Price	Availability	Quantity
10 mg	Inquiry	10-14 weeks
50 mg	Inquiry	10-14 weeks

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Product Introduction

Bioactivity

Description	Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).
In vitro	Opipramol inhibits the uptake of [^3H]DA in crude synaptosomal preparations, with an IC50 value of 5.5 μM [1].
In vivo	Opipramol (i.p.; 5-50 mg/kg) has been shown to enhance the release of dopamine in vivo [2].
Alias	Opipramol dihydrochloride, G-33040 dihydrochloride, Ensidon dihydrochloride

Chemical Properties

Molecular Weight	436.418
Formula	C₂₃H₃₁Cl₂N₃O
Cas No.	909-39-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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