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FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
(Synonyms: JTK4, HSFGFR3EX, FGFR3, FGFR2 α(IIIb), FGF R3, EC 2.7.10, CEK2, CEK, CD333, ACH) Copy Product InfoSynonyms: JTK4, HSFGFR3EX, FGFR3, FGFR2 α(IIIb), FGF R3, EC 2.7.10, CEK2, CEK, CD333, ACH
Catalog No. TMPK-00390 Copy Product Info
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $91 | 7-10 days | 7-10 days | |
| 10 µg | $148 | 7-10 days | 7-10 days | |
| 20 µg | $245 | 7-10 days | 7-10 days | |
| 50 µg | $483 | 7-10 days | 7-10 days | |
| 100 µg | $813 | 7-10 days | 7-10 days | |
| 200 µg | $1,470 | 7-10 days | 7-10 days | |
| 500 µg | $3,250 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Anti-FGFR3 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human FGFR3 alpha (IIIc) , His Tag with the EC50 of 35.9ng/ml determined by ELISA. |
| Description | FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | P22607-2 |
| Construction | Glu23-Gly377 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | JTK4, HSFGFR3EX, FGFR3, FGFR2 α(IIIb), FGF R3, EC 2.7.10, CEK2, CEK, CD333, ACH |
| Research Background | Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. |
| Molecular Weight | 41.4 kDa (predicted). Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight
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