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Anti-Stabilin-1 Polyclonal Antibody
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Catalog No. TMAB-01777
Alias Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1)
Anti-Stabilin-1 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-1. Anti-Stabilin-1 Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P,WB.
Anti-Stabilin-1 Polyclonal Antibody
Anti-Stabilin-1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01777Alias Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1)
Anti-Stabilin-1 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-1. Anti-Stabilin-1 Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Stabilin-1 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-1. Anti-Stabilin-1 Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1) |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Horse,Cow,Rat,Human) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. |
| Immunogen | KLH conjugated synthetic peptide: human stabilin1 |
| Antigen Species | Human |
| Gene Name | STAB1 |
| Gene ID | |
| Protein Name | Stabilin-1 |
| Uniprot ID | |
| Function | Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. |
| Molecular Weight | Theoretical: 273 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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