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Anti-YAP1 Antibody (3O376)
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Catalog No. TMAC-04307
Anti-YAP1 Antibody (3O376) is a Mouse antibody targeting YAP1. Anti-YAP1 Antibody (3O376) can be used in WB,IP,IF.
Anti-YAP1 Antibody (3O376)
Anti-YAP1 Antibody (3O376)
😃Good
Catalog No. TMAC-04307
Anti-YAP1 Antibody (3O376) is a Mouse antibody targeting YAP1. Anti-YAP1 Antibody (3O376) can be used in WB,IP,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-YAP1 Antibody (3O376) is a Mouse antibody targeting YAP1. Anti-YAP1 Antibody (3O376) can be used in WB,IP,IF. |
| Clone | 3O376 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of YAP expression in non-transfected 293T (A), human YAP transfected 293T (B) and Caco-2 (C) whole cell lysates. |
| Application | |
| Recommended Dose | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Yes-associated protein, otherwise known as YAP, is a 14-3-3-bindingmolecule that was originally recognized by virtue of its ability to bind to theSH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylationof a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. Thehighly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation,cell cycle progression and apoptosis by binding intracellular phosphoproteinsinvolved in signal transduction. YAP may link events at the plasmamembrane and cytoskeleton to inhibition of transcription in the nucleus in amanner regulated by 14-3-3 proteins. YAP shares homology with the WWdomain of TAZ, transcriptional co-activator with PDZ-binding motif, whichfunctions as a transcriptional co-activator by binding to the PPXY motif presentin transcription factors. YAP is expressed at high levels in the lung, placenta,prostate, ovary and testis. |
| Conjucates | Unconjugated |
| Immunogen | Amino acids 294-323 within an internal region of YAP of human origin |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 65 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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