CEACAM6 Protein, Cynomolgus, Recombinant (His)

Name: CEACAM6 Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPY-05850
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)) Copy Product Info

Synonyms: carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

Catalog No. TMPY-05850 Copy Product Info

Purity: 99.3%

CEACAM6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.3 kDa and the accession number is XP_005589488.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$47	-	In Stock
10 µg	$74	7-10 days	7-10 days
20 µg	$118	-	In Stock
50 µg	$228	-	In Stock
100 µg	$405	7-10 days	7-10 days
200 µg	$716	7-10 days	7-10 days
500 µg	$1,520	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.3%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Immobilized TPP-3310 derived Anti-CEACAM-6 antibody at 2 μg/mL (100 μL/well) can bind Recombinant Cynomolgus CEACAM6 Protein (His Tag) (Cat#TMPY-05850), the EC50 is 2.3-8.0 ng/mL (QC tested).
Description	CEACAM6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.3 kDa and the accession number is XP_005589488.1.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	XP_005589488.1
Construction	A DNA sequence encoding the cynomolgus CEACAM6 (XP_005589488.1) (Met1-Pro323) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Gln 35
Protein Purity	≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Research Background	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.

Chemical Properties

Molecular Weight

33.3 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.