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TargetMol | Compound Library

Toxic Compound Library

Catalog No. L5500

TargetMol's Toxic Compound Library include 1520 synthetic and natural toxic substances that can alter cellular, metabolic and membrane functions, such as DNA/ RNA synthesis inhibitors, cytotoxic agents, immune suppressants, anti-proliferatives, endocrine disruptors and other agents. This special collection finds application in testing the sensitivity, development and profiling of new assays in high throughput screening (HTS) programs used in new drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5500

Toxic Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1520 toxic substances for high throughput screening (HTS) and high content screening (HCS);
  • Covers various disease research areas, such as Cancer, Metabolism, Immunology and Cardiovascular system, etc.
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Antibacterial
Antibiotic
5-HT Receptor
Adrenergic Receptor
Endogenous Metabolite
Dopamine Receptor
Parasite
DNA/RNA Synthesis
Potassium Channel
COX
AChR
Histamine Receptor
HIV Protease
Sodium Channel
Calcium Channel
ROS
Cytochromes P450
SARS-CoV
NF-κB
Topoisomerase
Virus Protease
Ferroptosis
VEGFR
Antifungal
Mitophagy
Serotonin Transporter
Estrogen/progestogen Receptor
RAAS
GABA Receptor
Reactive Oxygen Species
c-Kit
Influenza Virus
Nucleoside Antimetabolite/Analog
HCV Protease
PDE
EGFR
Microtubule Associated
PDGFR
Norepinephrine
Akt
iGluR
Cholinesterase (ChE)
Estrogen Receptor/ERR
Interleukin
Reverse Transcriptase
ribosome
HSV
Dehydrogenase
PPAR
Glucocorticoid Receptor
p38 MAPK
ERK
FGFR
PI3K
FLT
c-Met/HGFR
TNF
Opioid Receptor
JAK
Angiotensin-converting Enzyme (ACE)
MMP
MRP
Caspase
Bcr-Abl
HMG-CoA Reductase
Src
HDAC
DNA Alkylator/Crosslinker
TLR
TRP/TRPV Channel
JNK
MAO
HIF/HIF Prolyl-Hydroxylase
Proton pump
Prostaglandin Receptor
Nrf2
Anti-infection
Antifolate
HBV
NO Synthase
STAT
Thrombin
Monoamine Oxidase
Progesterone Receptor
ALK
Drug Metabolite
Antifection
Androgen Receptor
ATPase
Carbonic Anhydrase
Phosphatase
Raf
CDK
AMPK
c-RET
Adenosine Receptor
PARP
Bcl-2 Family
Tyrosine Kinases
mTOR
CFTR
P-gp
Transferase
MEK
NMDAR
DPP-4
DNA gyrase
Endothelin Receptor
Factor Xa
IL Receptor
Trk receptor
Ras
GluR
Glutathione Peroxidase
PKC
SGLT
DHFR
HSP
Phospholipase
GNRH Receptor
ROS Kinase
LPL Receptor
ABC Transporter
glycosidase
Leukotriene Receptor
CaMK
DNA Methyltransferase
Thyroid hormone receptor(THR)
TAM Receptor
HIF
P2Y Receptor
S1P Receptor
ADC Cytotoxin
Antioxidant
Wnt/beta-catenin
Monoamine Transporter
Hydroxylase
HER
NADPH
ROCK
Molecular Glues
Telomerase
Antiviral
Beta Amyloid
Reductase
DNA Alkylation
Neurokinin receptor
Isocitrate Dehydrogenase (IDH)
Mitochondrial Metabolism
Kras
Histone Methyltransferase
P2X Receptor
Ligands for E3 Ligase
Thrombopoietin Receptor
Chloride channel
MTP
Xanthine Oxidase
Free radical scavengers
Retinoid Receptor
Glucosidase
Hedgehog/Smoothened
IκB/IKK
GPCR
BTK
Lipoxygenase
Aromatase
Melanocortin Receptor
MDM-2/p53
Serine Protease
Gamma-secretase
OAT
Fatty Acid Synthase
Histone Demethylase
PERK
CCR
DNA
Melatonin Receptor
Guanylate cyclase
FKBP
Tyrosinase
Na-K-Cl cotransporter
AhR
Proteasome
Integrin
GSK-3
Vitamin
IKZF
ASBT
Adenylate cyclase
UGT
Aurora Kinase
Cuproptosis
Protease-activated Receptor
IGF-1R
Sigma receptor
Imidazoline Receptor
MALT
Aryl Hydrocarbon Receptor
IRE1
LDL
GluCls
Pyroptosis
CGRP Receptor
PKM
Cell wall
MT Receptor
Tie-2
Integrase
Smo
Epigenetic Reader Domain
Decarboxylase
FOXO
Adenosine Deaminase
Rho
PAK
Vasopressin Receptor
Ephrin Receptor
GST
Gap Junction Protein
NOD
IRAK
ROR
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
Immunology/Inflammation related
PANoptosis
RSV
c-Fms
Complement System
Syk
PGC-1α
CRM1
Glutaminase
RIP kinase
GlyT
Somatostatin
Mucin
Wee1
BCRP
PGE Synthase
Survivin
Aquaporin
Hydrogenase
LTR
NR4A
Adiponectin Receptor
PROTAC Linker
FAAH
ATP Citrate Lyase
Sirtuin
Casein Kinase
CRISPR/Cas9
Monocarboxylate transporter
Cysteine Protease
FXR
Bradykinin Receptor
CXCR
Epoxide Hydrolase
OXPHOS
STING
NADPH-oxidase
p53
IFNAR
Necroptosis
OCT
RANKL/RANK
GRK
ACK1
transporter
PDK
S6 Kinase
NOD-like Receptor (NLR)
NPC1L1
DNA-PK
TOPK
PKA
LDLR
CSF-1R
Myosin
TGF-beta/Smad
Beta-Secretase
Na+/Ca2+ Exchanger
c-Myc
Photosensitizer
HCN Channel
cAMP
Histone Acetyltransferase
CRFR
Platelet aggregation
PD-1/PD-L1
Chk
DUB
MAPK
GPCR19
PLK