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ATP disodium trihydrate

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Catalog No. T64980Cas No. 51963-61-2
Alias Adenosine-5'-triphosphate disodium trihydrate

ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammation, which provides energy for the body's metabolism and also acts as a coenzyme in cells.

ATP disodium trihydrate

ATP disodium trihydrate

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Purity: 99.98%
Catalog No. T64980Alias Adenosine-5'-triphosphate disodium trihydrateCas No. 51963-61-2
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammation, which provides energy for the body's metabolism and also acts as a coenzyme in cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30In StockIn Stock
50 mg$37In StockIn Stock
100 mg$51In StockIn Stock
500 mg$81In StockIn Stock
1 g$117In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.98%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammation, which provides energy for the body's metabolism and also acts as a coenzyme in cells.
In vitro
ATP disodium trihydrate (5 mM; 1 h) with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.[3]
ATP disodium trihydrate (2 mM; 0.5-24 h) induces BMDM to secrete IL-1β, KC and MIP-2 in a caspase-1 activation-dependent manner.[4]
ATP disodium trihydrate promotes neutrophil chemotaxis.[4]
In vivo
ATP disodium trihydrate (50 mg/kg; ip) protects mice against bacterial infection and induces the secretion of IL-1β, KC, and MIP-2, promoting neutrophil recruitment.[4]
SynonymsAdenosine-5'-triphosphate disodium trihydrate
Chemical Properties
Molecular Weight605.19
FormulaC10H20N5Na2O16P3
Cas No.51963-61-2
SmilesO[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[Na+].O.[Na+].O.O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 0.9 mg/mL (1.49 mM), Sonication and heating to 80℃ are recommended.
H2O: 225 mg/mL (371.78 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM1.6524 mL8.2619 mL16.5237 mL82.6187 mL
H2O
1mg5mg10mg50mg
5 mM0.3305 mL1.6524 mL3.3047 mL16.5237 mL
10 mM0.1652 mL0.8262 mL1.6524 mL8.2619 mL
20 mM0.0826 mL0.4131 mL0.8262 mL4.1309 mL
50 mM0.0330 mL0.1652 mL0.3305 mL1.6524 mL
100 mM0.0165 mL0.0826 mL0.1652 mL0.8262 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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