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Anti-SFRP1 Antibody (3A606)
😃Good
Catalog No. TMAY-01056
Alias secreted frizzled-related protein 1, SARP2, FrzA, FRP-1, FRP1, FRP
Anti-SFRP1 Antibody (3A606) is a Rabbit antibody targeting SFRP1. Anti-SFRP1 Antibody (3A606) can be used in ELISA.
Anti-SFRP1 Antibody (3A606)
Anti-SFRP1 Antibody (3A606)
😃Good
Catalog No. TMAY-01056Alias secreted frizzled-related protein 1, SARP2, FrzA, FRP-1, FRP1, FRP
Anti-SFRP1 Antibody (3A606) is a Rabbit antibody targeting SFRP1. Anti-SFRP1 Antibody (3A606) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | secreted frizzled-related protein 1, SARP2, FrzA, FRP-1, FRP1, FRP |
| Ig Type | Rabbit IgG |
| Clone | 3A606 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SFRP1 (rh SFRP1; TMPY-00918; NP_003003.3; Met1-Lys314). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Secreted frizzled-related protein 1, also known as sFRP1, is a 35 kDa prototypical member of the SFRP family. SFRP family consists of five secreted glycoproteins in humans acting as extracellular signaling ligands. Each is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs act as soluble modulators of Wnt signaling, counteracting Wnt-induced effects at high concentrations and promoting them at lower concentrations. SFRPs are able to bind Wnt proteins and Fz receptors in the extracellular compartment. The interaction between SFRPs and Wnt proteins prevents the latter from binding the Fz receptors. The Wnt pathway plays a key role in embryonic development, cell differentiation and cell proliferation. The deregulation of this critical developmental pathway occurs in several human tumor entities. Mouse sFRP1 is highly expressed in kidney and embryonic heart, as well as in the eye, where it is principally localized to the ciliary body and the lens epithelium. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SFRP1 Protein (TMPY-00918) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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