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[D-Trp34]-Neuropeptide Y Acetate

🥰Excellent
Catalog No. TP1984L
Alias [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)

[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y Acetate markedly increases food intake in rats.

[D-Trp34]-Neuropeptide Y Acetate
Other Forms of [D-Trp34]-Neuropeptide Y Acetate:
[D-Trp34]-Neuropeptide YTP1984153549-84-9
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[D-Trp34]-Neuropeptide Y Acetate

🥰Excellent
Purity: 99.73%
Catalog No. TP1984LAlias [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)
[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y Acetate markedly increases food intake in rats.
Pack SizePriceAvailabilityQuantity
1 mg$117In Stock
5 mg$270In Stock
10 mg$405In Stock
25 mg$692In Stock
50 mg$1,030In Stock
100 mg$1,550In Stock
200 mg$2,080In Stock
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Purity:99.73%
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Product Introduction

Bioactivity
Description
[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y Acetate markedly increases food intake in rats.
In vitro
[D-Trp34]-Neuropeptide Y Acetate exhibits pKi values of 6.49, 5.43, 7.08, 7.53, 6.55, 5.95, 6.85, 7.41 for hY1, hY2, hY4, hY5, rY1, rY2, rY4, rY5 in CHO cells. [D-Trp34]-Neuropeptide Y Acetate exhibits pEC50 values of 6.44, <6, 6.28，7.82 for rY1, rY2 in CHO cells and rY4, rY5 in HEK-293 cells[1].
In vivo
[D-Trp34]-Neuropeptide Y Acetate (0, 8 and 16 μg/rat; I.C.V) stimulats food intake to the same extent in both lean and obese rats 1 h after injection at a dose of 16 μg in male Zucker rats[2].
Synonyms[D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)
Chemical Properties
Molecular Weight4371.78
FormulaC198H293N55O58
SmilesCC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H]2CCCN2C([C@@H](NC([C@@H](NC([C@@H]3CCCN3C([C@@H](NC([C@@H](NC([C@@H]4CCCN4C([C@@H](N)CC5=CC=C(O)C=C5)=O)=O)CO)=O)CCCCN)=O)=O)CC(O)=O)=O)CC(N)=O)=O)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)C)=O)=O)C)=O)CCC(O)=O)=O)CC(O)=O)=O)CC(C)C)=O)C)=O)CCCNC(N)=N)=O)CC6=CC=C(O)C=C6)=O)CC7=CC=C(O)C=C7)=O)CO)=O)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CC8=CNC=N8)=O)CC9=CC=C(O)C=C9)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N)=O)CC%10=CC=C(O)C=C%10)=O)CCCNC(N)=N)=O)CC%11=CNC%12=CC=CC=C%12%11)=O)CCCNC(N)=N)=O)[C@H](O)C)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(N)=O)=O)C.CC(O)=O
Relative Density.no data available
SequenceH-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-D-Trp-Arg-Tyr-NH2
Sequence ShortYPSKPDNPGEDAPAEDLARYYSALRHYINLITR-{D-Trp}-RY-NH2
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

NeuropeptideYReceptorNeuropeptide Y Receptorneuropeptide Y (NPY) Y5 receptor153549-84-9 Free base153549-84-9[D-Trp34]-Neuropeptide Y Acetate
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