CDH10 Protein, Human, Recombinant (His)

Name: CDH10 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07161
Rating: 4.5 (1 reviews)

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Catalog No. TMPY-07161 Copy Product Info

CDH10 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9Y6N8.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$77	7-10 days	7-10 days
10 µg	$126	7-10 days	7-10 days
20 µg	$198	7-10 days	7-10 days
50 µg	$397	7-10 days	7-10 days
100 µg	$796	7-10 days	7-10 days
200 µg	$1,200	7-10 days	7-10 days
500 µg	$2,590	7-10 days	7-10 days
1 mg	$5,280	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CDH10 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9Y6N8.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q9Y6N8
Construction	Gly55-Ala613
Protein Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Research Background	Cadherin 10 (CDH10) is a type II cadherin predominantly expressed in the brain, putatively involved in axon outgrowth and guidance. Also known to mediate calcium-dependent cell-cell adhesion and maintain the correct balance between excitation and inhibition in neuronal dendrites., CDH 10 has a large N-terminal extracellular domain (containing 5 cadherin motif subdomains which appear to determine the specificity of the protein's homophilic cell adhesion activity), a single membrane-spanning domain, and a small, conserved C-terminal cytoplasmic domain. CDH10 spans 157.7kb on chromosome 5 and produces two transcript variants. Mutations and loss of expression of this protein have been observed in multiple cancer types, including gastric, colorectal, pancreatic, endometrial and lung. Genetic variations nearby the CDH10 genetic region have been associated with autism.

Chemical Properties

Molecular Weight

63.81 kDa (predicted); 72-82 kDa (reducing contition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.