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Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody
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Catalog No. TMAC-02659
Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MSK2 (Thr568). Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody can be used in WB,IHC.
Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody
Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody
😃Good
Catalog No. TMAC-02659
Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MSK2 (Thr568). Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MSK2 (Thr568). Anti-Phospho-MSK2 (Thr568) Polyclonal Antibody can be used in WB,IHC. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-3000; IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14). In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro-inflammatory cytokines. Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 568 (M-Q-T(p)-P-C) derived from Human MSK2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 95 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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