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(S)-Purvalanol B

Name: (S)-Purvalanol B
Brand: TargetMol
SKU: T13454
Rating: 4.5 (1 reviews)

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Catalog No. T13454Cas No. 2310135-61-4

Alias (S)-NG 95

(S)-Purvalanol B, the S enantiomer of Purvalanol B, is an inhibitor of cyclin-dependent kinase (CDK).

(S)-Purvalanol B

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Catalog No. T13454Alias (S)-NG 95Cas No. 2310135-61-4

(S)-Purvalanol B, the S enantiomer of Purvalanol B, is an inhibitor of cyclin-dependent kinase (CDK).

Pack Size	Price	Availability
25 mg	Inquiry	3-6 months
50 mg	Inquiry	3-6 months
100 mg	Inquiry	3-6 months

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	(S)-Purvalanol B, the S enantiomer of Purvalanol B, is an inhibitor of cyclin-dependent kinase (CDK).
Synonyms	(S)-NG 95

Chemical Properties

Molecular Weight	432.9
Formula	C₂₀H₂₅ClN₆O₃
Cas No.	2310135-61-4
Relative Density.	1.43 g/cm3 at 20℃ (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 76.7 mg/mL (177.18 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3100 mL	11.5500 mL	23.1000 mL	115.5001 mL
5 mM	0.4620 mL	2.3100 mL	4.6200 mL	23.1000 mL
10 mM	0.2310 mL	1.1550 mL	2.3100 mL	11.5500 mL
20 mM	0.1155 mL	0.5775 mL	1.1550 mL	5.7750 mL
50 mM	0.0462 mL	0.2310 mL	0.4620 mL	2.3100 mL
100 mM	0.0231 mL	0.1155 mL	0.2310 mL	1.1550 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc