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Anti-PCK1 Antibody (7Q973) (Synonyms: Serine-protein kinase PCK1, Phosphoenolpyruvate carboxykinase, cytosolic ...)
Catalog No. TMAC-03096 Copy Product Info
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Anti-PCK1 Antibody (7Q973) is a Rabbit antibody targeting PCK1. Anti-PCK1 Antibody (7Q973) can be used in ICC,IHC,WB.
Anti-PCK1 Antibody (7Q973)
Copy Product Info🥰Excellent
Catalog No. TMAC-03096
Synonyms Serine-protein kinase PCK1, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, PEPCK1, PCK1, cytosolic [GTP]
Anti-PCK1 Antibody (7Q973) is a Rabbit antibody targeting PCK1. Anti-PCK1 Antibody (7Q973) can be used in ICC,IHC,WB.
Anti-PCK1 Antibody
(7Q973)
(7Q973)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-PCK1 Antibody (7Q973) is a Rabbit antibody targeting PCK1. Anti-PCK1 Antibody (7Q973) can be used in ICC,IHC,WB. |
| Synonyms | Serine-protein kinase PCK1, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, PEPCK1, PCK1, cytosolic [GTP] |
| Ig Type | IgG |
| Clone | 7Q973 |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-PCK1 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PCK1 antibody. Counter stained with hematoxylin. 3. ICC staining PCK1 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining PCK1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining PCK1 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.      |
| Application | |
| Recommended Dose | IHC: 1:50-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Normal adjustment to changes in blood glucose levels depends on insulin signaling as well as enzymes involved in the regulation of gluconeogenesis. Pathological changes to this process are central to the type 2 diabetes phenotype. Phosphoenolpyruvate carboxykinase (PEPCK) plays an important role in this process by stimulating hepatic glucose production. PEPCK expression increases in response to glucagon and glucocorticoids, while insulin suppresses expression. Modulation of the signals governing PEPCK levels present a potential therapeutic approach to the treatment of insulin resistance and consequently obesity. The cytosolic form of PEPCK, known as PEPCK-C, and the mitochondrial form, known as PEPCK-M, are encoded by two different nuclear genes in mouse, human and chicken. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 69 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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