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Anti-NKG2D/CD314 Antibody-HRP (1H699)
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Catalog No. TMAY-00989H
Alias NKG2-D, NKG2D, KLR, killer cell lectin-like receptor subfamily K, member 1, D12S2489E, CD314
Anti-NKG2D/CD314 Antibody-HRP (1H699) is a HRP-conjugated Mouse antibody targeting NKG2D/CD314. Anti-NKG2D/CD314 Antibody-HRP (1H699) can be used in ELISA.
Anti-NKG2D/CD314 Antibody-HRP (1H699)
Anti-NKG2D/CD314 Antibody-HRP (1H699)
😃Good
Catalog No. TMAY-00989HAlias NKG2-D, NKG2D, KLR, killer cell lectin-like receptor subfamily K, member 1, D12S2489E, CD314
Anti-NKG2D/CD314 Antibody-HRP (1H699) is a HRP-conjugated Mouse antibody targeting NKG2D/CD314. Anti-NKG2D/CD314 Antibody-HRP (1H699) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $292 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | NKG2-D, NKG2D, KLR, killer cell lectin-like receptor subfamily K, member 1, D12S2489E, CD314 |
| Ig Type | Mouse IgG3 |
| Clone | 1H699 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NKG2D/CD314/KLRK1 (rh NKG2D/CD314/KLRK1; TMPY-03256; P26718-1; Phe78-Val216). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human NKG2D/CD314/KLRK1 Protein (TMPY-03256) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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