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Anti-SOX-2 Antibody (7C478)
😃Good
Catalog No. TMAY-00056
Anti-SOX-2 Antibody (7C478) is a Rabbit antibody targeting SOX-2. Anti-SOX-2 Antibody (7C478) can be used in IHC-P.
Anti-SOX-2 Antibody (7C478)
Anti-SOX-2 Antibody (7C478)
😃Good
Catalog No. TMAY-00056
Anti-SOX-2 Antibody (7C478) is a Rabbit antibody targeting SOX-2. Anti-SOX-2 Antibody (7C478) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SOX-2 Antibody (7C478) is a Rabbit antibody targeting SOX-2. Anti-SOX-2 Antibody (7C478) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7C478 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human SOX2 in human testis with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SOX2 in human brain with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the human Sox2. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SOX2 is a member of the SOXB1 subfamily of transcription factors most notably involved in the reprogramming of somatic cells into induced pluripotent stem cells. Housed on chromosome 3, the SOX2 gene encodes for a protein with a C-terminal transcriptional activation domain and a DNA-binding HMG domain that contains a nuclear localization/export signal. SOX2 forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development and pluripotency such as YES1, FGF4, UTF1 and ZFP206. Mutations in this gene have been associated with bilateral eye disease. SOX2 antigen and antibody were found in small-cell lung cancer cell lines and sera. However, neither exists in normal sera, suggesting that SOX2 might be a potential tumor target or marker. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the human Sox2. |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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